M. Fukusaki et al., SYMPTOMS OF SPINAL STENOSIS DO NOT IMPROVE AFTER EPIDURAL STEROID INJECTION, The Clinical journal of pain, 14(2), 1998, pp. 148-151
Objective: This study was carried out to evaluate the therapeutic effe
ct of epidural steroid injection on pseudoclaudication in patients wit
h lumbar degenerative spinal canal stenosis. Design: Fifty-three patie
nts who complained of pseudoclaudication of less than 20 m in walking
distance were randomly divided into three groups. Group 1 (n = 16) und
erwent epidural injection with 8 ml of saline. Group 2 (n = 18) underw
ent epidural block with 8 ml of 1% mepivacaine. Group 3 (n = 19) under
went epidural block with a combination of 8 ml of 1% mepivacaine and 4
0 mg of methylprednisolone. The criteria of evaluation were as follows
: excellent effect, >100 m in walking distance; good effect, 20-100 m
in walking distance; poor effect, <20 m in walking distance. Results:
In group 1, the numbers of patients who showed a good effect were two
(12.5%) after 1 week, one (6.5%) after 1 month, and one (6.5%) after 3
months. In group 2, the numbers of patients who showed a good or exce
llent result were 10 (55.5%) after 1 week, three (16.7%) after 1 month
, and one (5.6%) after 3 months. In group 3, the numbers of patients w
ho showed a good or excellent result were 12 (63.2%) after 1 week, thr
ee (15.8%) after 1 month, and one (5.3%) after 3 months. There was no
significant difference in the effectiveness of treatment between group
2 and group 3 throughout the time course. Conclusion: The results sug
gest that epidural steroid injection has no beneficial effect on the p
seudoclaudication associated with spinal canal stenosis as compared wi
th epidural block with a local anesthetic alone.