REACTIVITY AND SUITABILITY OF T-BOC-PROTECTED THIOPHOSPHOTYROSINE INTERMEDIATE ANALOGS FOR THE SOLID OR SOLUTION-PHASE PEPTIDE-SYNTHESIS

toxycarbonyl)-O-(dimethylthiophosphono)-L-tyrosine (6) and ycarbony)-O -(dicyanoethylthiophosphono)-L-tyrosine (15) were prepared as intermed iates for the synthesis of thiophosphotyrosine-containing peptides. Th e reactivity and suitability of two compounds for the solid phase or s olution phase peptide synthesis utilizing t-Boc chemistry were examine d.