BRANCHIAL CLEFT CYST CARCINOMA - MYTH OR REALITY

Citation
B. Singh et al., BRANCHIAL CLEFT CYST CARCINOMA - MYTH OR REALITY, The Annals of otology, rhinology & laryngology, 107(6), 1998, pp. 519-524
Citations number
16
Categorie Soggetti
Otorhinolaryngology
ISSN journal
00034894
Volume
107
Issue
6
Year of publication
1998
Pages
519 - 524
Database
ISI
SICI code
0003-4894(1998)107:6<519:BCCC-M>2.0.ZU;2-#
Abstract
Skepticism has surrounded the existence of branchial cleft carcinoma s ince the entity was first described in 1882. However, a landmark work of 1950 established four criteria for the diagnosis of branchial cleft carcinoma, the most important criterion being histologic proof of car cinoma arising from a normal cyst epithelium. Of the 43 cases found in an extensive review of the literature, only 7 cases have satisfied al l four of the criteria. To this we add 2 patients who had recurrent in fections of a cervical cyst as children and later developed carcinoma within these structures. Additionally, we propose a minor modification to the 1950 criteria and a paradigm for diagnosis and management of t hese lesions.