The author describes a method of comparing sequences of characters, ca
lled sequence alignment or string matching, and illustrates its use in
the analysis of daily activity patterns derived from time-use diaries
. It allows definition of measures of similarity or distance between c
omplete sequences, called global alignment, or the evaluation of the b
est fit of short sequences within long sequences, called local alignme
nt. Alignments may be done pairwise to develop similarity or distance
matrices that describe the relatedness of individuals in the set of se
quences being examined. Pairwise alignment methods may be extended to
many individuals by using multiple alignment analysis. A number of ele
mentary hand-worked examples are provided. The basic concepts are disc
ussed in terms of the problems of time-use research and the method is
illustrated by examining diary data from a survey conducted in Reading
, England. The CLUSTAL software used for the alignments was written fo
r molecular biological research. The method offers a powerful techniqu
e for analyzing the full richness of diary data without discarding the
details of episode ordering, duration, or transition. It is also poss
ible to extend the analysis to include the context of activities, such
as the presence of other persons or the location, but such extensions
would require software designed for social science rather than bioche
mical problems. The method also offers a challenge to researchers to b
egin to develop theories about the determinants of daily behavior as a
whole, rather than about participation in single activities or about
time-budget totals.