Rn. Townsend et al., TIMING FRACTURE REPAIR IN PATIENTS WITH SEVERE BRAIN INJURY (GLASGOW COMA SCALE SCORE LESS-THAN-9), The journal of trauma, injury, infection, and critical care, 44(6), 1998, pp. 977-982
Background: Trauma patients with severe brain injury are at risk of se
condary brain injury, Femur fractures, if present, should be repaired
when potential causes of secondary brain injury have been corrected. M
ethods: Sixty-one patients with severe or moderate closed head injury
and femur fractures were identified, Patients were divided into groups
by time until femur fracture reduction. Results: An inversely proport
ional trend was demonstrated when comparing time until surgery with th
e percentage of patients who experienced hypotensive events during sur
gery, Patients in the 0- to 2-hour group were eight times more likely
to become hypotensive during femur repair than patients in the > 24-ho
ur group. Seventy-four percent of patients with intracranial pressure
monitoring experienced cerebral perfusion pressure < 70 mm Hg. Conclus
ions: Operation in similar patients should be done when risks are mini
mized by adequate resuscitation, Secondary brain injury is more common
in early femur repair, Operation delay of 24 hours may be necessary t
o prevent hypoxia, hypotension, and low cerebral perfusion pressure.