M. Joubert et al., EXTENSION OF AN ACINAR CELL-CARCINOMA OF THE PANCREAS WITH CYSTIC CHANGES INTO THE MAIN PANCREATIC DUCT, Gastroenterologie clinique et biologique, 22(4), 1998, pp. 465-468
We report a case of acinar cell carcinoma of the pancreas with mislead
ing cystic changes. A 32-year-old woman presented with symptoms sugges
ting acute pancreatitis on chronic pancreatitis. The abdominal compute
d tomography and the endoscopic retrograde pancreatography demonstrate
d hypertrophy of the pancreatic head associated with global dilatation
of main pancreatic duct and secondary canals and a 5 cm communicating
cyst A intraductal papillary-mucinous tumor was suggested. Microscopi
c findings showed a poorly differentiated adenocarcinoma. Six month la
ter, a liver metastasis was detected. The microscopic appearance was d
ifferent, suggesting acinar cell carcinoma, confirmed by immunohistoch
emistry. Only two other cases of acinar cell carcinoma with cystic com
ponent have been reported in the literature.