El. Bradley et al., DIAGNOSIS AND INITIAL MANAGEMENT OF BLUNT PANCREATIC TRAUMA - GUIDELINES FROM A MULTIINSTITUTIONAL REVIEW, Annals of surgery, 227(6), 1998, pp. 861-868
Objective The authors' objective was to resolve the current controvers
ies sies surrounding the diagnosis and management of blunt pancreatic
trauma (BPT). Summary Background Data The diagnosis of BPT is notoriou
sly difficult serum amylase has been claimed to be neither sensitive n
or specific, and recent anecdotal reports have suggested a role for co
mputed tomography. The therapy of BPT has been controversial, with som
e suggesting selective observation and others advocating immediate exp
loration to prevent a delay-induced escalation in morbidity and death.
Methods The authors conducted a retrospective chart review of documen
ted BPT from six institutions, using a standardized binary data form c
omposed of 187 items and 237 data fields. Results A significant correl
ation between pancreas-specific: morbidity and injury to the main panc
reatic duct (MPD) was noted. Patients requiring delayed surgical inter
vention after an unsuccessful period of observation demonstrated notab
ly higher pancreas-specific mortality and morbidity rates, principally
because of the incidence of unrecognized injuries to the MPD. Althoug
h detection of MPD injuries by computed tomography was no better than
flipping a coin, endoscopic pancreatography was accurate in each of th
e five cases in which it was used. Conclusions The principal cause of
pancreas-specific morbidity after BPT is injury to the MPD. Parenchyma
l pancreatic injuries not involving the ductal system rarely result in
pancreas-specific morbidity or death. Delay in recognizing MPD injury
leads to increased mortality and morbidity rates. CT is unreliable in
diagnosing MPD injury and should not be used to guide therapy. Initia
l selection of patients with isolated BPT for observation or surgery c
an be based on the determination of MPD integrity.