Prevalence of overweight among the general population has been reporte
d to be 33% for males and 36% for females. We undertook this study to
establish overweight prevalence data in a cohort with Down syndrome an
d to stratify the incidence of overweight by living arrangement. We me
asured Body Mass Index (BMI) in 283 persons with Down syndrome and fou
nd a higher prevalence of overweight in this group compared to the gen
eral population. Individuals with Down syndrome living in a family set
ting had a higher incidence of overweight than did those living in a g
roup home setting. Overweight prevalence among persons with Down syndr
ome should be considered a major public health concern that warrants f
urther attention from researchers, practitioners, family members, and
individuals with Down syndrome.