Molluscum contagiosum of the sole is extremely rare and only three cas
es have been reported in the literature. We report a solitary giant mo
lluscum contagiosum on the left sole of a 5-year-old boy, which should
be clinically differentiated from plantar wart, eccrine poroma, epide
rmal cyst, foreign body granuloma, cryptococcal infection, and pyogeni
c granuloma.