G. Kampf et al., PREVALENCE AND RISK-FACTORS FOR NOSOCOMIAL LOWER RESPIRATORY-TRACT INFECTIONS IN GERMAN HOSPITALS, Journal of clinical epidemiology, 51(6), 1998, pp. 495-502
The prevalence and risk factors for nosocomial lower respiratory tract
infections (LRTI) in Germany were determined as part of a national su
rvey on nosocomial infections. The study included 14,966 patients in 7
2 representatively selected hospitals with departments of general medi
cine, surgery, obstetrics, gynecology, and intensive care units (ICU).
Surveillance was carried out by four previously validated medical doc
tors who strictly applied the CDC criteria for diagnosis of nosocomial
infections. The overall prevalence of hospital-acquired LRTI was 0.72
% with the highest rate in hospitals with more than 600 beds (1.08%) a
nd among the patients on intensive care units (9.00%). Ventilator-asso
ciated pneumonia rates were highest in patients on ICUs (13.27). Polyt
rauma, impaired consciousness, chronic airway disease, prior surgery,
and cardiovascular disease were significantly related to the occurrenc
e of nosocomial LRTI. P. aeruginosa was the predominant organism causi
ng nosocomial LRTI. Nosocomial LRTI remain a problem mainly on ICUs. P
atients at risk should be monitored with extra care. (C) 1998 Elsevier
Science Inc.