BORNA-DISEASE IN A DOG WITH LETHAL MENINGOENCEPHALITIS

Authors
WEISSENBOCK H NOWOTNY N CAPLAZI P KOLODZIEJEK J EHRENSPERGER F
Citation
H. Weissenbock et al., BORNA-DISEASE IN A DOG WITH LETHAL MENINGOENCEPHALITIS, Journal of clinical microbiology, 36(7), 1998, pp. 2127-2130
Citations number
24
Categorie Soggetti
Microbiology
Journal title
Journal of clinical microbiology → ACNP
ISSN journal
00951137
Volume
36
Issue
7
Year of publication
1998
Pages
2127 - 2130
Database
ISI
SICI code
0095-1137(1998)36:7<2127:BIADWL>2.0.ZU;2-I
Abstract
A dog was euthanatized because of progressive neurological signs. Hist ologically, a nonsuppurative meningoencephalitis was found. By immunoh istochemistry, in situ hybridization, and nested PCR procedures, Borna disease virus (BDV) antigen and BDV-specific RNA were demonstrated in brain tissues of the dog. The nucleotide sequence of the PCR product showed 94 to 98% homology to published BDV sequences. This is the firs t description of Borna disease in a dog.