PROTEIN DESIGN - A PERSPECTIVE FROM SIMPLE TRACTABLE MODELS

Authors
SHAKHNOVICH EI
Citation
Ei. Shakhnovich, PROTEIN DESIGN - A PERSPECTIVE FROM SIMPLE TRACTABLE MODELS, Folding & design, 3(3), 1998, pp. 45-58
Citations number
90
Categorie Soggetti
Biology,Biophysics
Journal title
Folding & design → ACNP
ISSN journal
13590278
Volume
3
Issue
3
Year of publication
1998
Pages
45 - 58
Database
ISI
SICI code
1359-0278(1998)3:3<45:PD-APF>2.0.ZU;2-P
Abstract
Recent progress in computational approaches to protein design builds o n advances in statistical mechanical protein folding theory. Here, the number of sequences folding into a given conformation is evaluated an d a simple condition for a protein model's designability is outlined. (C) Current Biology Ltd ISSN 1359-0278.