Mh. Elnagdi et al., THE REACTION OF PHENACYL MALONONITRILE WITH HYDRAZINES - SYNTHESIS OFNEW PYRIDAZINONES AND PYRAZOLO[1,5-A]PYRIMIDINES, Gazzetta chimica italiana, 127(12), 1997, pp. 791-794
The reaction of phenacylmalononitrile with hydrazine hydrate affords a
mixture of 3,5-diamino-4-phenacylpyrazole, 2, and -phenyl-1,4,5,6-tet
raydropyridazine-5-carbonitrile 5. The reaction of 2 with a variety of
reagents, that enabled the synthesis of some new pyrazolo[1,5-a]pyrim
idine derivatives, is described.