THE REACTION OF PHENACYL MALONONITRILE WITH HYDRAZINES - SYNTHESIS OFNEW PYRIDAZINONES AND PYRAZOLO[1,5-A]PYRIMIDINES

Authors
ELNAGDI MH ELGHAMRY I KANDEEL E RAHMAN AHA ALNAGGAR AA AMER S RIAD M
Citation
Mh. Elnagdi et al., THE REACTION OF PHENACYL MALONONITRILE WITH HYDRAZINES - SYNTHESIS OFNEW PYRIDAZINONES AND PYRAZOLO[1,5-A]PYRIMIDINES, Gazzetta chimica italiana, 127(12), 1997, pp. 791-794
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Gazzetta chimica italiana → ACNP
ISSN journal
00165603
Volume
127
Issue
12
Year of publication
1997
Pages
791 - 794
Database
ISI
SICI code
0016-5603(1997)127:12<791:TROPMW>2.0.ZU;2-D
Abstract
The reaction of phenacylmalononitrile with hydrazine hydrate affords a mixture of 3,5-diamino-4-phenacylpyrazole, 2, and -phenyl-1,4,5,6-tet raydropyridazine-5-carbonitrile 5. The reaction of 2 with a variety of reagents, that enabled the synthesis of some new pyrazolo[1,5-a]pyrim idine derivatives, is described.