Jm. Dupuis et al., MAGNETIC-RESONANCE-IMAGING IN CARDIAC SAR COIDOSIS - A CASE-REPORT, Archives des maladies du coeur et des vaisseaux, 87(1), 1994, pp. 105-110
The authors report the value of magnetic resonance imaging (MRI) in a
case of cardiac sarcoidosis presenting with syncopal ventricular tachy
cardia (VT). The images were acquired in a monomorphic multiplane echo
spin sequence. A 25 millisecond interval was chosen for the weighted
T1 sequence. A second weighted T2 sequence using an interval of 70 mil
liseconds was then performed. The acquisitions were recorded in these
planes axial, sagittal and coronal. The thickness of the sections was
8 mm. MRI was useful in locating the exact site and extent of the lesi
ons; this enabled the operators to perform <<guided>> endomyocardial b
iopsies. In the weighted T1 sequences, these biopsies showed zones of
increased intramyocardial signal density, more pronounced on the secon
d weighted T2 sequences. Moreover, it was possible to follow up the ou
tcome of these lesions with steroid therapy and observe their partial
regression. These non-specific appearances may be observed in all infl
ammatory conditions but, in the context of systemic sarcoidosis, are v
ery suggestive of cardiac involvement. In view of the clinical latency
of cardiac sarcoidosis and its poor prognosis, the non-invasive chara
cter of MRI should make this a routine investigation in all patients w
ith systemic sarcoidosis.