NUCLEAR-ENVELOPE AND NUCLEAR-PORE ASSEMBLY - ANALYSIS OF ASSEMBLY INTERMEDIATES BY ELECTRON-MICROSCOPY

At mitosis, the nucleus of higher eukaryotic cells disassembles into c omponents which subsequently reform functional nuclear envelopes in th e two daughter cells. The molecular mechanisms underlying this remarka ble morphological reorganization are the focus of active investigation . Recent electron microscopy techniques have provided intriguing glimp ses of intermediate structures in both nuclear envelope and nuclear po re complex reassembly.