Nc. Spitzer, SPONTANEOUS CA2- SIGNALING SYSTEMS FOR DIFFERENTIATION( SPIKES AND WAVES IN EMBRYONIC NEURONS ), Trends in neurosciences, 17(3), 1994, pp. 115-118
Many excitable cells are specialized to promote Ca2+ influx at early s
tages of development. This article focuses an spontaneous fluctuations
of intracellular Ca2+ that are observed during this period. Removal o
f Ca2+ or suppression of influx alters subsequent differentiation. Thu
s these signals appear to regulate aspects of early maturation.