M. Schmid et al., GAMMA-KNIFE RADIOSURGERY AND ALBENDAZOLE FOR CEREBRAL ALVEOLAR HYDATID-DISEASE, Clinical infectious diseases, 26(6), 1998, pp. 1379-1382
Standard treatment of cerebral alveolar hydatid disease consists of op
en brain surgery and systemic albendazole. We describe a patient with
inoperable cerebral alveolar hydatid cysts on whom gamma knife radiosu
rgery was used instead of open brain surgery. Because of the size of t
he multicystic lesion, the gamma knife procedure was done in two sessi
ons. Repeated courses of albendazole were given concurrently. Magnetic
resonance imaging follow-up studies showed marked shrinkage of the ir
radiated cystic structures and initially increased perifocal edema. At
a follow-up visit 3 years after gamma knife radiosurgery, the polycys
tic lesion, the perifocal edema, and the neurological symptoms had all
markedly decreased. The patient is now stable and has minimal neurolo
gical symptoms, and the quality of her life has improved. Gamma knife
radiosurgery may be an alternative for patients with cerebral alveolar
hydatid disease for whom surgery is not possible.