GAMMA-KNIFE RADIOSURGERY AND ALBENDAZOLE FOR CEREBRAL ALVEOLAR HYDATID-DISEASE

Citation
M. Schmid et al., GAMMA-KNIFE RADIOSURGERY AND ALBENDAZOLE FOR CEREBRAL ALVEOLAR HYDATID-DISEASE, Clinical infectious diseases, 26(6), 1998, pp. 1379-1382
Citations number
17
Categorie Soggetti
Infectious Diseases",Immunology,Microbiology
ISSN journal
10584838
Volume
26
Issue
6
Year of publication
1998
Pages
1379 - 1382
Database
ISI
SICI code
1058-4838(1998)26:6<1379:GRAAFC>2.0.ZU;2-6
Abstract
Standard treatment of cerebral alveolar hydatid disease consists of op en brain surgery and systemic albendazole. We describe a patient with inoperable cerebral alveolar hydatid cysts on whom gamma knife radiosu rgery was used instead of open brain surgery. Because of the size of t he multicystic lesion, the gamma knife procedure was done in two sessi ons. Repeated courses of albendazole were given concurrently. Magnetic resonance imaging follow-up studies showed marked shrinkage of the ir radiated cystic structures and initially increased perifocal edema. At a follow-up visit 3 years after gamma knife radiosurgery, the polycys tic lesion, the perifocal edema, and the neurological symptoms had all markedly decreased. The patient is now stable and has minimal neurolo gical symptoms, and the quality of her life has improved. Gamma knife radiosurgery may be an alternative for patients with cerebral alveolar hydatid disease for whom surgery is not possible.