ANTISPERM ANTIBODIES IN MEN WITH PSYCHOGENIC ANEJACULATION

Antisperm autoantibodies were determined in 16 men suffering from psyc hogenic anejaculation who underwent assisted reproduction treatments. Blood and semen samples were collected after transrectal electroejacul ation and antisperm antibodies in serum and on the surface of motile s permatozoa were measured using the direct and indirect immunobead bind ing test. Five men (31%) were found positive for antisperm antibodies. The majority of antibodies were directed against the sperm heads. Sur face antibodies were mainly IgA isotype whereas serum antibodies were IgG isotype. These results suggest that psychogenic anejaculation migh t be associated with increased incidence of antisperm autoimmunity.