The purpose of this research was to investigate the effect of hypofunc
tion of the thyroid gland, caused by radioactive suppression of the gl
and, on the pattern of spermatozoa motility in different segments of t
he rat epididymis. Thyroidectomy was obtained by i.p. infection of 270
mu Ci of I-131. After about 30 days, the animal reached hypothyroidis
m as determined by serum level of T-4. When the motility pattern of th
e sperm obtained from the epididymis of normal rats was compared to th
at of hypothyroid animals, a drop in the parameter of path velocity (V
AP), progressive velocity (VSL), and track speed (VCL) were detected.
Hypofunction was associated with decreasing sperm motility in the epid
idiymis. In thyroidectomized rats injected with T-4, no sperm motility
changes were observed.