LIPOSOMES CONTAINING AMPHIPHILES PREPARED BY USING A LIPOPHILIC CHAINTRANSFER REAGENT - RESPONSIVENESS TO EXTERNAL STIMULI

Authors
KITANO H MAEDA Y TAKEUCHI S IEDA K AIZU Y
Citation
H. Kitano et al., LIPOSOMES CONTAINING AMPHIPHILES PREPARED BY USING A LIPOPHILIC CHAINTRANSFER REAGENT - RESPONSIVENESS TO EXTERNAL STIMULI, Langmuir, 10(2), 1994, pp. 403-406
Citations number
20
Categorie Soggetti
Chemistry Physical
Journal title
Langmuir → ACNP
ISSN journal
07437463
Volume
10
Issue
2
Year of publication
1994
Pages
403 - 406
Database
ISI
SICI code
0743-7463(1994)10:2<403:LCAPBU>2.0.ZU;2-E
Abstract
A lipophilic chain transfer reagent was prepared by coupling of N,N-di octadecylamine with 3-mercaptopropionic acid, and telomerization of ac rylic acid (product, DODA-S-PAA) or N-isopropylacrylamide (product, DO DA-S-PIPA) was carried out by using the chain transfer reagent. The am phiphiles obtained formed stable liposomes with lecithin (L-alpha-dimy ristoylphosphatidylcholine or L-alpha-dipalmitoylphosphatidylcholine), and the liposomes showed a pH-responsive (DODA-S-PAA) or temperature- responsive (DODA-S-PIPA) release of fluorophore from inner water pool. The lipophilic chain transfer reagent was useful to prepare amphiphil es with various functionalities.