CLONING AND EXPRESSION OF AZ2, A PUTATIVE ZINC-FINGER TRANSCRIPTION FACTOR FROM DROSOPHILA-MELANOGASTER

Citation
A. Mccormack et al., CLONING AND EXPRESSION OF AZ2, A PUTATIVE ZINC-FINGER TRANSCRIPTION FACTOR FROM DROSOPHILA-MELANOGASTER, Development, genes and evolution, 208(3), 1998, pp. 172-174
Citations number
7
Categorie Soggetti
Developmental Biology","Cell Biology","Biology Miscellaneous
ISSN journal
0949944X
Volume
208
Issue
3
Year of publication
1998
Pages
172 - 174
Database
ISI
SICI code
0949-944X(1998)208:3<172:CAEOAA>2.0.ZU;2-V
Abstract
A Drosophila gene (az2), mapping to a cluster of embryonic lethals at 43BC on the polytene chromosomes, has been sequenced and found to enco de a predicted protein with six consecutive C2H2 zinc finger domains, The carboxy-terminus of az2 is related to a number of Drosophila and m ammalian transcription factors. The 5' end of the gene is unrelated to genes in the databases. The gene is expressed in the adult female, in both the carcass and ovary, but is most abundant in the ovary. It is expressed in the nurse cells and transported to the oocyte.