Purpose: To describe the results of management of glass intraocular fo
reign bodies (IOFBs). Methods: A total of 51 eyes of 43 patients that
sustained penetrating injury with glass IOFB were studied retrospectiv
ely. A total of 23.5% had IOFB only in the anterior segment; the rest
had IOFB in the posterior segment alone or in both the anterior and po
sterior segments. Six eyes were followed conservatively despite IOFB i
n a functional eye. Removal of IOFB was combined with repair of retina
l detachment (where present) using internal tamponade with gas or sili
cone oil or buckle. Results: After a mean follow-up of 16.8 months, 66
.7% of eyes recovered better than 6/60 (20/200) vision and 75.6% had a
ttached retina. On univariate analysis, scleral entry wound, posterior
segment IOFB, larger size of IOFB, and retinal damage were found to b
e associated with poor anatomic outcome. Lower presenting visual acuit
y, hyphema, retinal damage, subretinal hemorrhage, detached retina, an
d larger IOFB were associated with a poor functional result. Multivari
ate analysis identified retinal damage caused by the foreign body as t
he only factor significantly associated with poor anatomic as well as
functional outcome. Conclusions: Glass IOFBs are caused in a majority
of cases by blast injury. Bilaterality is not uncommon. Presence of re
tinal damage is predictive of poor functional and anatomic results. Ov
erall results are modest with modern vitreoretinal surgical techniques
.