The increase of pollen-associated oral allergy syndrome on the one han
d and the observed increase in tree pollen counts on the other hand ar
e indicators for a direct chain of cause and effect. The observed incr
ease of pollen-associated oral allergy syndrome goes parallel with an
increase of pollen, especially tree pollen which are relevant for inha
lation allergy. During 15 years (1981-1995) the prevalence concerning
apple and nut oral allergy syndrome has increased from 17.3% to 58.3%.
The investigated tree pollen amount has increased during the period f
rom 1969 to 1996 between a factor from 2.5 to 6.1 depending from the t
ree type. The observed increase in the tree pollen amount may have dif
ferent causes among them climatical changes, increased input of nutrie
nts like CO2 or NOx but also a real increase of trees for example in p
arcs and avenues. The increase of pollen-associated oral allergy syndr
ome can hardly be explained by a change due to the eat habit. The incr
ease of tree pollen instead, is well documented. However it is well po
ssible that additional modifications of environmental factors might ha
ve influenced the aggressifity of pollen, but this was not the subject
of this investigation.