IgE-mediated sensitisation and allergic reactions as asthma and rhinit
is on enzymes are published. Also the early reaction on proteolytic en
zymes after ingestion is described or in other cases assumed. We inves
tigated seven patients with suspicion on IgE-mediated reaction on panc
reatin an enzyme combination. In four patients specific IgE-antibodies
were found by EAST. All patients suffered on pancreatin related asthm
a or rhinitis. In one patient later on an early phase-reaction after i
ngestion of pancreatin is described.