In many studies, multiple categorical responses or measurements are ma
de on members of different populations or treatment groups. This arise
s often in surveys where individuals may mark all answers that apply w
hen responding to a multiple-choice question. Frequently, it is of int
erest to determine whether the distributions of responses differ among
groups. In this situation, the test statistic of the usual Pearson ch
i-square test no longer measures a scaled distance between observed an
d hypothesized cell counts in a contingency table, and its distributio
n is no longer the familiar chi-square. This paper presents a modifica
tion to the Pearson statistic that measures the appropriate distance f
or multiple-response tables. The asymptotic distribution is shown to b
e that of a linear combination of chi-square random variables with coe
fficients depending on the true probabilities. A bootstrap resampling
method is proposed instead to obtain a null-hypothesis sampling distri
bution. Simulations show that this bootstrap method maintains its size
under a variety of circumstances, while a naively applied Pearson chi
-square test is severely affected by multiple responses.