ANTENATALLY DETECTED URINARY-TRACT ABNORMALITIES - CHANGING INCIDENCEAND MANAGEMENT

Citation
Ca. James et al., ANTENATALLY DETECTED URINARY-TRACT ABNORMALITIES - CHANGING INCIDENCEAND MANAGEMENT, European journal of pediatrics, 157(6), 1998, pp. 508-511
Citations number
22
Categorie Soggetti
Pediatrics
ISSN journal
03406199
Volume
157
Issue
6
Year of publication
1998
Pages
508 - 511
Database
ISI
SICI code
0340-6199(1998)157:6<508:ADUA-C>2.0.ZU;2-X
Abstract
To define the incidence of urinary tract abnormalities detected by ant enatal ultrasound and assess changes in postnatal management we conduc ted a retrospective survey using data bases of the nephro-urology unit , obstetric ultrasound and perinatal pathology departments. The birth population (105,542) of the two Nottingham teaching hospitals between January 1984 and December 1993 was divided into two 5-year cohorts, 19 84-1988 and 1989-1993. Detailed fetal scanning at 18-20 weeks gestatio n was introduced in 1989. During this 10-year period, 201 abnormalitie s of the urinary tract were noted with a 2:1 male to female ratio. The incidence of abnormalities in the first 5 years was 1 in 964 compared to 1 in 364 in the last 5 years. There was a significant increase in the number detected before 20 weeks gestation (12% in 1984-1988 compar ed to 62% in 1989-1993). Despite the increased incidence of abnormalit ies detected, the termination rate remained static between the two 5-y ear cohorts. Only 3 fetuses had intra-uterine intervention and 173 wer e live-born. Eight infants subsequently died in association with other major congenital abnormalities. The incidence of transient abnormalit ies (antenatal dilatation with no abnormality noted on postnatal ultra sound) increased from 6% in 1984-1988 to 18% in the 1989-1993 cohort. A more conservative approach to postnatal management is reflected by 7 1% of infants having operations between 1984 and 1988 compared to 35% in 1989-1993. Conclusion The advent of detailed fetal scanning at 18-2 0 weeks gestation has significantly increased the detection rate of ur inary tract abnormalities with no significant increase in pregnancy te rmination rates. The need for antenatal intervention is a rare event a nd most problems can be managed conservatively both pre- and postnatal ly.