Ca. James et al., ANTENATALLY DETECTED URINARY-TRACT ABNORMALITIES - CHANGING INCIDENCEAND MANAGEMENT, European journal of pediatrics, 157(6), 1998, pp. 508-511
To define the incidence of urinary tract abnormalities detected by ant
enatal ultrasound and assess changes in postnatal management we conduc
ted a retrospective survey using data bases of the nephro-urology unit
, obstetric ultrasound and perinatal pathology departments. The birth
population (105,542) of the two Nottingham teaching hospitals between
January 1984 and December 1993 was divided into two 5-year cohorts, 19
84-1988 and 1989-1993. Detailed fetal scanning at 18-20 weeks gestatio
n was introduced in 1989. During this 10-year period, 201 abnormalitie
s of the urinary tract were noted with a 2:1 male to female ratio. The
incidence of abnormalities in the first 5 years was 1 in 964 compared
to 1 in 364 in the last 5 years. There was a significant increase in
the number detected before 20 weeks gestation (12% in 1984-1988 compar
ed to 62% in 1989-1993). Despite the increased incidence of abnormalit
ies detected, the termination rate remained static between the two 5-y
ear cohorts. Only 3 fetuses had intra-uterine intervention and 173 wer
e live-born. Eight infants subsequently died in association with other
major congenital abnormalities. The incidence of transient abnormalit
ies (antenatal dilatation with no abnormality noted on postnatal ultra
sound) increased from 6% in 1984-1988 to 18% in the 1989-1993 cohort.
A more conservative approach to postnatal management is reflected by 7
1% of infants having operations between 1984 and 1988 compared to 35%
in 1989-1993. Conclusion The advent of detailed fetal scanning at 18-2
0 weeks gestation has significantly increased the detection rate of ur
inary tract abnormalities with no significant increase in pregnancy te
rmination rates. The need for antenatal intervention is a rare event a
nd most problems can be managed conservatively both pre- and postnatal
ly.