SYNTHESIS OF POLY(LACTIC ACID) BY DIRECT POLYCONDENSATION OF LACTIC-ACID USING 1,1'-CARBONYLDIIMIDAZOLE, N,N,N',N'-TETRAMETHYLCHLOROFORMAMIDINIUM CHLORIDE, AND N,N'-DICYCLOHEXYLCARBODIIMIDE AS CONDENSING AGENTS

Authors
AKUTSU F INOKI M UEI H SUEYOSHI M KASASHIMA Y NARUCHI K YAMAGUCHI Y SUNAHARA M
Citation
F. Akutsu et al., SYNTHESIS OF POLY(LACTIC ACID) BY DIRECT POLYCONDENSATION OF LACTIC-ACID USING 1,1'-CARBONYLDIIMIDAZOLE, N,N,N',N'-TETRAMETHYLCHLOROFORMAMIDINIUM CHLORIDE, AND N,N'-DICYCLOHEXYLCARBODIIMIDE AS CONDENSING AGENTS, Polymer Journal, 30(5), 1998, pp. 421-423
Citations number
26
Categorie Soggetti
Polymer Sciences
Journal title
Polymer Journal → ACNP
ISSN journal
00323896
Volume
30
Issue
5
Year of publication
1998
Pages
421 - 423
Database
ISI
SICI code
0032-3896(1998)30:5<421:SOPABD>2.0.ZU;2-B
Abstract
The direct polycondensation of racemic lactic acid using condensing ag ents, such as 1,1-carbonyldiimidazole (CDI), N,N,N',N'-tetramethylchlo roformamidinium chloride (TMCFAC), and '-dicyclohexylcarbodiimide/4-di methylaminopyridine (DCC/DMAP), was investigated. Reactions using CDI proceeded slightly. Polycondensation using TMCFAC with pyridine gave a polymer in 83% yield, but the number-average molecular weight ((M) ov er bar(n)) was 3700. Thus, TMCFAC is not effective in the direct polyc ondensation of lactic acid. However, DCC/DMAP is effective, and polyco ndensation in dichloromethane at room temperature for 24 h afforded po ly(lactic acid) having (M) over bar(n) of 15400 in 89% yield.