Objective: The purpose of this in vitro study was to evaluate some for
ms of preventing or avoiding demineralization within enamel cavity wal
ls adjacent to amalgam restorations. Method and materials: Third molar
teeth were sectioned to obtain 72 specimens, divided into one control
and five experimental groups: amalgam only; varnish plus amalgam; aci
dulated phosphate fluoride plus amalgam; adhesive amalgam; glass-ionom
er cement plus amalgam; control (amalgam only, not subjected to a demi
neralization challenge). The experimental groups were subjected to pH
and thermal cycling and then submitted to enamel hardness determinatio
ns. Results: Significant differences between the treatment groups reve
aled that the bonded amalgam technique offered the best resistance to
demineralization. The Else of cavity varnish resulted in greater miner
al loss than amalgam placed alone. Conclusion: The use of an adhesive
system, glass-ionomer cement, or acidulated phosphate fluoride under a
malgam restorations may interfere with development of secondary caries
.