A FACILE ACCESS TO ARYL ALPHA-SIALOSIDES - THE COMBINATION OF A VOLATILE AMINE BASE AND ACETONITRILE IN GLYCOSIDATION OF SIALOSYL CHLORIDES

Authors
KUBOKI A SEKIGUCHI T SUGAI T OHTA H
Citation
A. Kuboki et al., A FACILE ACCESS TO ARYL ALPHA-SIALOSIDES - THE COMBINATION OF A VOLATILE AMINE BASE AND ACETONITRILE IN GLYCOSIDATION OF SIALOSYL CHLORIDES, Synlett, (5), 1998, pp. 479
Citations number
70
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
5
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):5<479:AFATAA>2.0.ZU;2-Y
Abstract
We have succeeded in achieving a facile access to 4-nitrophenyl and 4- methylumbelliferyl-alpha-sialosides. To sialosyl chlorides which are f ully protected with acetyl groups as glycosyl donors, the action of ph enols with diisopropylethylamine in acetonitrile brought about high yi eld as well as facile product isolation.