DIASTEREOSELECTIVE ADDITION OF SILYL ENOL ETHER TO CHIRAL IMINES AND 1,3-OXAZOLIDINES USING A LEWIS-ACID

Authors
HIGASHIYAMA K KYO H TAKAHASHI H
Citation
K. Higashiyama et al., DIASTEREOSELECTIVE ADDITION OF SILYL ENOL ETHER TO CHIRAL IMINES AND 1,3-OXAZOLIDINES USING A LEWIS-ACID, Synlett, (5), 1998, pp. 489
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
5
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):5<489:DAOSEE>2.0.ZU;2-G
Abstract
The Lewis acid promoted reaction of silyl enol ether to chiral imines and 1,3-oxazolidines derived from (R)-phenylglycinol afforded with goo d diastereoselectivity the (R,R)-beta-amino ester derivatives from the imines, and the (R,S)-beta-amino ester derivatives from the 1,3-oxazo lidines.