Background: Hip fractures are an important cause of death and function
al dependence in the United States. Purpose: To review the evidence fo
r clinical decisions that medical consultants make for patients with h
ip fracture and to develop recommendations for care.Data Sources: Publ
ished reports of clinical studies were found by searching MEDLINE and
selected bibliographies. Study Selection: Studies were included if dat
a were presented on clinical interventions to improve care of conditio
ns typically encountered by medical consultants in the care of patient
s with hip fracture. Such conditions include timing of surgery, infect
ion prophylaxis, thromboembolic prophylaxis, postoperative nutritional
management, urinary tract management, prevention and management of de
lirium, application and timing of rehabilitation services, and prevent
ion of subsequent falls. Meta-analyses; randomized, controlled trials;
or other controlled studies were included if possible. If no such tri
als were identified, the best evidence from studies with other designs
was included. Data Extraction: Interventions were selected on the bas
is of their efficacy or potential efficacy in improving functional out
come. Trials with positive and negative results were compared for diff
erences in intervention and strength of study methods. Data Synthesis:
Strong evidence supports medical recommendations for decisions about
timing and duration of prophylactic antibiotics, selection of thromboe
mbolic prophylaxis, urinary tract and nutritional management, and reha
bilitative services. Many case series support early surgical repair, a
lthough patients who would benefit from delay and further medical work
-up have not been well identified. Evidence for decisions about assess
ment of subsequent risk for fall and risk for and management of deliri
um is based largely on data from patients without hip fracture but is
probably applicable. Future research should target optimal duration of
thromboembolic prophylaxis, cost-effectiveness of low-molecular-weigh
t heparin compared with that of other thromboembolic prophylactic regi
mens, management of delirium, rehabilitative services, and efficacy of
assessment of risk for later falls. Conclusions: The data suggest tha
t evidence-based medical care can improve hip fracture outcomes. The m
edical consultant has a key role in providing this care and managing t
he preoperative conditions and postoperative complications that may af
fect optimal functional recovery.