TOWARDS POLYKETIDE LIBRARIES - II - SYNTHESIS OF CHIRAL ARACEMIC DIKETIDES AND TRIKETIDES ON A SOLID SUPPORT

Authors
REGGELIN M BRENIG V WELCKER R
Citation
M. Reggelin et al., TOWARDS POLYKETIDE LIBRARIES - II - SYNTHESIS OF CHIRAL ARACEMIC DIKETIDES AND TRIKETIDES ON A SOLID SUPPORT, Tetrahedron letters, 39(27), 1998, pp. 4801-4804
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
27
Year of publication
1998
Pages
4801 - 4804
Database
ISI
SICI code
0040-4039(1998)39:27<4801:TPL-I->2.0.ZU;2-S
Abstract
A new fluoride ion cleavable linker serves as starter unit for iterati ve asymmetric aldol reactions on a solid support. The synthetic protoc ol relies on the baron enolate chemistry of D. A. Evens and a cyclic r eestablishment of key functionalities. It entails the opportunity for the generation of di-and triketide libraries. (C) 1998 Elsevier Scienc e Ltd. All rights reserved.