A CONCISE SYNTHESIS OF AZA-DIPEPTIDE ISOSTERES

Authors
FASSLER A BOLD G STEINER H
Citation
A. Fassler et al., A CONCISE SYNTHESIS OF AZA-DIPEPTIDE ISOSTERES, Tetrahedron letters, 39(27), 1998, pp. 4925-4928
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
27
Year of publication
1998
Pages
4925 - 4928
Database
ISI
SICI code
0040-4039(1998)39:27<4925:ACSOAI>2.0.ZU;2-I
Abstract
Aza-dipeptide isosteres as potent HIV-protease inhibitors containing a (hydroxyethyl)-hydrazine moiety are synthesised in >98% diastereomeri c and enantiomeric purity starting from (L)-phenylalanine aldehyde. (C ) 1998 Elsevier Science Ltd. All rights reserved.