NEW CYCLOARTANOL SULFATES FROM THE ALGA TYDEMANIA-EXPEDITIONIS - INHIBITORS OF THE PROTEIN-TYROSINE KINASE PP60(V-SRC)

Authors
GOVINDAN M ABBAS SA SCHMITZ FJ LEE RH PAPKOFF JS SLATE DL
Citation
M. Govindan et al., NEW CYCLOARTANOL SULFATES FROM THE ALGA TYDEMANIA-EXPEDITIONIS - INHIBITORS OF THE PROTEIN-TYROSINE KINASE PP60(V-SRC), Journal of natural products, 57(1), 1994, pp. 74-78
Citations number
15
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
57
Issue
1
Year of publication
1994
Pages
74 - 78
Database
ISI
SICI code
0163-3864(1994)57:1<74:NCSFTA>2.0.ZU;2-4
Abstract
Bioactivity-directed fractionation of the extracts of the green alga T ydemania expeditionis using the protein tyrosine kinase pp60(v-src) le d to the isolation of three new cycloartanol disulfates, 1-3, which sh ow modest inhibition of this enzyme. The structures were deduced by sp ectroscopic methods.