K. Ekdahl et al., LIMITING THE SPREAD OF PENICILLIN-RESISTANT STREPTOCOCCUS-PNEUMONIAE - EXPERIENCES FROM THE SOUTH SWEDISH PNEUMOCOCCAL INTERVENTION PROJECT, Microbial drug resistance, 4(2), 1998, pp. 99-105
In an attempt to limit the spread of penicillin-resistant pneumococci
(PRP), an intervention project was initiated in the Malmohus County, s
outhern Sweden in January 1995, The ongoing project combines tradition
al communicable disease control measures and actions aiming at reducin
g antibiotics consumption, All patients in the county with a nasophary
ngeal culture positive for PRP with MIC of Penicillin G greater than o
r equal to 0.5 mg/L are followed with nasopharyngeal cultures until PR
P-negative, Nasopharyngeal cultures are obtained from family members a
nd close contacts of the index cases, Preschool children carrying PRP
are denied attendance at group day-care. From January 1995 to March 19
97, 1,038 PRP-carriers (429 index cases and 609 contact cases) were id
entified. Children aged 1-6 years dominated (83%), Antibiotics sales d
ecreased during the study period, and epidemiologic data indicate that
the intervention may have limited the dissemination of PRP in the cou
nty, but further evaluation is needed.