The role and contributions of the Philadelphia Orthopedic Hospital and
Infirmary for Nervous Diseases in the development of neurology in 19t
h-century America are described. American neurology was largely born d
uring the Civil War through the work of S.W. Mitchell at Turner's Lane
Hospital. With the closing of this military facility, the United Stat
es was left without an institution dedicated to neurologic research an
d the treatment of nervous system diseases. Nineteenth century archiva
l data, including original Trustees' minutes, annual board of managers
reports, patient case books, and published research from the Philadel
phia Orthopedic Hospital and Infirmary for Nervous Diseases were studi
ed. The Philadelphia Orthopedic Hospital and Infirmary for Nervous Dis
eases promoted the development of neurology in the United States throu
gh three main activities. First, it offered patients with primary nerv
ous system diseases, arthritis, and orthopedic disorders specialized c
are that was unavailable at medical universities. Second, its medical
staff, especially Mitchell, provided opportunities for advanced neurol
ogic education. Postgraduate physicians interested in neurologic disea
se attended formal lectures and directly participated in the operation
of outpatient clinics and inpatient rounds. Finally, its formalized r
ecord system in the form of case books facilitated neurologic research
. These records formed the basis of landmark publications by Mitchell,
Sinkler, Osler, and others on rest therapy, spastic palsies, chorea,
and other topics. As America's first and comprehensive peacetime neuro
logic facility, the Philadelphia Orthopedic Hospital and Infirmary for
Nervous Diseases fostered the evolution of neurology as a separate, v
iable specialty in the post-Civil War period and provided a particular
focus for the study of interactions among orthopedic, nutritional, an
d neurologic disorders.