COMPARATIVE-STUDY OF GUIDED BONE REGENERATION USING ABSORBABLE AND PERMANENT BARRIER MEMBRANES - A HISTOLOGIC REPORT

In an experimental study using the Gottingen minipig, Gore-Tex, Gore R esolut, and Vicryl barrier membranes were tested for their efficacy in guided bone regeneration. The results were compared to those of autol ogous periosteum. The strongest reossification was seen in the bone de fects covered with Gore-Tex; however time-dependent disintegration phe nomena, which had already been observed in preliminary examinations, w ere clearly established. After investigations of cell cultures to whic h human macrophages were added, the latter findings can be interpreted as the result of a physicochemical process, since a direct attack by the macrophages was not seen in vitro. Of the membranes used, the abso rbable ones tended to collapse, depending on the size of the defect th at was used, and they did not enhance reossification as much as did th e permanent membranes. The periosteum-covered defects showed a satisfa ctory degree of regeneration, and no differences were observed between freely transplanted and pedunculated periosteum.