Ab. Novaes et al., IMMEDIATE IMPLANTS PLACED INTO INFECTED SITES - A HISTOMORPHOMETRIC STUDY IN DOGS, The International journal of oral and maxillofacial implants, 13(3), 1998, pp. 422-427
To study the effect of chronically infected sites on the immediate pla
cement of implants, periapical lesions were induced in the third and f
ourth premolars of four dogs and the contralateral teeth were used as
controls. Nine months after the induction of periapical lesions, exper
imental and control teeth were extracted, and 28 IMZ implants were imm
ediately placed. After a healing period of 12 weeks, the animals were
sacrificed, the hemi-mandibles were removed, and specimens were prepar
ed to be hard-sectioned and stained with toluidine blue. All areas hea
led without inflammation or exudation and all implants were clinically
immobile and were radiographically determined to be surrounded by nor
mal-appearing bone. Histologically, there were no signs of infection,
and the histomorphometric analyses revealed that 28.6% and 38.7% had o
sseointegrated for the experimental and control implants, respectively
. The difference was not statistically significant. It was concluded t
hat chronically infected sites, such as those showing signs of periapi
cal pathosis, may not be a contraindication for immediate implants, if
certain clinical measures and preoperative and postoperative care are
taken.