A. Jainkittivong et al., THE RELATIONSHIP BETWEEN SALIVARY HISTATIN LEVELS AND ORAL YEAST CARRIAGE, Oral microbiology and immunology, 13(3), 1998, pp. 181-187
Citations number
32
Categorie Soggetti
Immunology,Microbiology,"Dentistry,Oral Surgery & Medicine
Candida species are common commensal inhabitants of the oral cavity. H
uman saliva contains antifungal proteins called histatins. We tested t
he hypothesis that oral yeast status is related to salivary histatin l
evels. Thirty subjects were divided into two groups based on the prese
nce (n=15) or absence (n=15) of yeast on oral mucosa surfaces. Unstimu
lated and stimulated submandibular and sublingual and parotid saliva w
as collected from each subject. Salivary flow rates were measured and
histatin concentrations were determined in the stimulated saliva sampl
es. The yeast colony positive group showed lower median unstimulated p
arotid saliva flow rates as well as lower median concentrations of tot
al histatins in submandibular and sublingual saliva. There was a negat
ive correlation between yeast colony-forming units and unstimulated pa
rotid saliva flow rates and between yeast colony-forming units and sub
mandibular and sublingual saliva histatin concentration and secretion.
The results suggest that oral yeast status may be influenced by unsti
mulated parotid saliva flow rates and by submandibular and sublingual
histatin concentration and secretion.