DOES A RELATIONSHIP EXIST BETWEEN TRENDS IN ESTROGEN-RECEPTOR LEVELS AND BREAST-CANCER INCIDENCE AND MORTALITY

Authors
CELENTANO E MONTELLA M BONELLI P CECCO L DEMARCO M DICINTIO P IANNUZZO M TUCCILLO F BOTTI G DAIUTO G
Citation
E. Celentano et al., DOES A RELATIONSHIP EXIST BETWEEN TRENDS IN ESTROGEN-RECEPTOR LEVELS AND BREAST-CANCER INCIDENCE AND MORTALITY, International journal of oncology, 13(1), 1998, pp. 129-135
Citations number
55
Categorie Soggetti
Oncology
Journal title
International journal of oncology → ACNP
ISSN journal
10196439
Volume
13
Issue
1
Year of publication
1998
Pages
129 - 135
Database
ISI
SICI code
1019-6439(1998)13:1<129:DAREBT>2.0.ZU;2-Z
Abstract
Estrogen receptor data from 4,049 patients with primary breast cancer treated at the National Cancer Institute of Naples between 1984 and 19 96, have been evaluated to analyze temporal trend of this tumor marker . The prevalence rate of estrogen receptor levels falls from >75% in w omen older than 60 years to <70% in younger patients. The analysis of these data by birth cohort shows a trend very similar to that of breas t cancer incidence in Italy, suggesting that the breast cancer appeara nce could be modulated in different period of life.