M. Dellomo et al., PREVENTIVE MEASURES REDUCE EXPOSURE TO POLYCYCLIC AROMATIC-HYDROCARBONS AT A GRAPHITE ELECTRODE PLANT, Occupational and environmental medicine, 55(6), 1998, pp. 401-406
Objective-This study assessed the efficacy of preventive measures in a
graphite electrode plant aimed at reducing occupational exposure to p
olycyclic aromatic hydrocarbons (PAHs). Methods-Electrode workers (n=1
46) answered a questionnaire and provided an end of shift urine sample
. Urinary 1-hydroxypyrene (1-hp(ur)), a biological marker of exposure
to PAHs, was measured by high performance liquid chromatography couple
d with: (a) fluorescence detection. 1-Hydroxypyrene concentrations wer
e compared with the concentrations measured before implementing the pr
eventive measures; and (b) those of a control group of 54 men not occu
pationally exposed to PAHs. Results-After implementation of preventive
measures, median concentrations 1-hp,, were significantly reduced in
some groups of workers: by -24%, -37% and -30% in workers at the green
electrode unit, one baking impregnation unit, and the laboratory, res
pectively. In workers at a second baking impregnation unit, in end pro
duct finishing and in the power station 1-hp,, concentrations were unc
hanged. Urinary 1-hp concentrations were still significantly higher in
each group of workers than in the control group (p<0.001 for any comp
arison). Concentrations in the workers varied with the type of jab, th
e highest values being found in workers engaged in the power station,
in the two baking impregnation units and in the green electrode unit.
Conclusions-Implementing preventive measures significantly reduced exp
osure to PAHs at a graphite electrode plant. The reduction in median a
nd peak concentrations of 1-hp,, which reflects total exposure to, and
internal dose of PAHs, was most evident in workers employed in the un
its where preventive measures had been taken. Despite an overall reduc
tion, further preventive measures are needed to minimise exposure to P
AHs and consequently the risk of adverse health effects.