THERAPEUTIC AMNIOINFUSIONS AND FETAL FIBRONECTIN PATTERN IN A CASE WITH PRETERM RUPTURED MEMBRANES THAT RESEALED

Objective: Determination of fetal fibronectin (fFN) levels in a patien t at risk of preterm delivery and having premature rupture of the memb ranes. Patient and Methods: The present case report concerns a pregnan t woman with premature rupture of the membranes at 16 weeks of gestati on who was submitted to repeated therapeutic transabdominal amnioinfus ions and had a spontaneous resolution of the rupture at 32 weeks of ge station. Results: A good pregnancy outcome was observed. High cervicov aginal fFN levels were observed during the period of membrane rupture with following drop of fFN levels during this period and spontaneous r eseal of the membranes. Conclusions: Active expectant management, usin g repeated amnioinfusions, probably played a useful role in the therap eutic success of this pregnancy. Further, fFN was a reliable marker of the rupture of membranes. The possible role of fFN in the clinical ma nagement of high-risk pregnancies is confirmed.