Menstrual disorders in adolescents should be investigated promptly to
avoid or alleviate possible long-term sequelae, including impaired fer
tility. Patients with uterine amenorrhea cannot become pregnant. The p
rognosis for later fertility in patients with oligoamenorrheas depends
on the pathogenesis and degree of the condition. Hypothalamic oligoam
enorrheas generally resolve when the offending stimuli are removed, an
d the prognosis for future fertility is good. In patients with pituita
ry lesions, even those with complete loss of pituitary function, pregn
ancies can be achieved and maintained with exogenous gonadotropins. Me
nstrual disorders due to hyperprolactinemia can be treated effectively
. Hyperandrogenemic oligoamenorrheas, especially the polycystic ovary
syndrome, are common. Future fertility has been improved with preventi
ve measures in adolescence and later interventions. Patients with prim
ary ovarian insufficiency and persisting hypergonadotropic amenorrhea
have a poor prognosis. A new aspect is the restitution of ovarian func
tion after treatments for malignant diseases.