THE INTERACTION BETWEEN LEPTIN AND THE HYPOTHALAMIC-PITUITARY-THYROIDAXIS

The description of the adipose tissue hormone leptin has led to import ant discoveries. Leptin plays a role not only in the regulation of met abolic efficiency, energy expenditure, food intake and adiposity, but also contributes greatly to the adaptation of the organism to starvati on, Much of the literature has focused on the physiologic roles of lep tin-driven processes as diverse as feeding behavior, body weight, defe nse to starvation and reproduction, The following discussion summarize s knowledge that has accumulated regarding the interaction between lep tin and the hypothalamic-pituitary-thyroid axis.