OPTIMIZATION OF THE DEPOSITED POWER DISTRIBUTION INSIDE A LAYERED LOSSY MEDIUM IRRADIATED BY A COUPLED SYSTEM OF CONCENTRICALLY PLACED WAVE-GUIDE APPLICATORS
Ks. Nikita et al., OPTIMIZATION OF THE DEPOSITED POWER DISTRIBUTION INSIDE A LAYERED LOSSY MEDIUM IRRADIATED BY A COUPLED SYSTEM OF CONCENTRICALLY PLACED WAVE-GUIDE APPLICATORS, IEEE transactions on biomedical engineering, 45(7), 1998, pp. 909-920
A method is proposed for controlling the deposited power distribution
in a layered cylindrical lossy model, irradiated by a phased-array hyp
erthermia system consisting of four waveguide applicators. A rigorous
electromagnetic model of the heated tissue, which takes into account c
oupling phenomena between system elements, is used for predicting the
electric held at any point inside tissue, The relative amplitudes and
relative phases of the array elements are optimized in order to attain
desired specific absorption rate (SAR) distributions inside and outsi
de malignant tissues. A constrained nonlinear optimization problem is
solved by using the penalty function method and the resulting unconstr
ained minimization of the penalty function is carried out by the downh
ill simplex method. Two practical phased-array hyperthermia systems ha
ve been studied and numerical results are presented.