Jc. Lo et al., RIEDELS THYROIDITIS PRESENTING WITH HYPOTHYROIDISM AND HYPOPARATHYROIDISM - DRAMATIC RESPONSE TO GLUCOCORTICOID AND THYROXINE THERAPY, Clinical endocrinology, 48(6), 1998, pp. 815-818
Riedel's thyroiditis is a rare fibro-inflammatory process originating
in the thyroid gland with progressive extension and invasion of surrou
nding tissues. Patients frequently present with a stony hard thyroid m
ass suggestive of anaplastic carcinoma. We report a striking case of R
iedel's thyroiditis associated with hypothyroidism, hypoparathyroidism
and bilateral vocal cord paralysis. A dramatic response to high dose
prednisone and levothyroxine therapy was seen, with recovery of parath
yroid and vocal cord function. Our case suggests that early initiation
of combination therapy may be important, particularly in the presence
of severe disease.