Sm. Anand et Sm. Jain, SYNTHESIS OF ISOETOPOSIDE AND ISOTENIPOSIDE, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 37(4), 1998, pp. 391-393
Condensation of glucosides of;podophyllotoxin 4 and 4'-demethylpodophy
llotoxin 5 with diethyl acetal in dry nitromethane and thiophene-2-car
boxaldehyde yield the corresponding acetals namely, isoetoposide methy
l ether 6, isoetoposide 7 and isoteniposide 8.