Hn. Gopi et Vvs. Babu, SYNTHESIS OF PEPTIDES MEDIATED BY POTASSIUM-SALT OF 1-HYDROXY-7-AZABENZOTRIAZOLE, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 37(4), 1998, pp. 394-396
The potassium salt of 1-hydroxy-7-azabenzotriazole can be used along w
ith acid chlorides of 9-fluorenylmethyloxycarbonylamino acids as coupl
ing agents in peptide bond formation. The acylation reactions are rapi
d and efficient and can be carried out in an organic medium. The yield
s as well as purity of the peptides are satisfactory.