SYNTHESIS OF OLIGOSACCHARIDES OF BIOLOGICAL IMPORTANCE

Citation
Pj. Garegg et al., SYNTHESIS OF OLIGOSACCHARIDES OF BIOLOGICAL IMPORTANCE, Pure and applied chemistry, 70(2), 1998, pp. 293-298
Citations number
29
Categorie Soggetti
Chemistry
Journal title
ISSN journal
00334545
Volume
70
Issue
2
Year of publication
1998
Pages
293 - 298
Database
ISI
SICI code
0033-4545(1998)70:2<293:SOOOBI>2.0.ZU;2-C
Abstract
Syntheses of a variant of myo-inositol-containing compounds are discus sed and described, including glycan phosphatidylinositol structures fo und on various cell surfaces and believed to play important roles in t he life cycles of tropical parasites (Trypanosoma and Leishmania) and in the action of insulin, and phosphatidyl inositol phosphates, known signal substances in a number of biological events. The resolution of myo-inositol is performed using camphor acetals and the phosphodiester linkages are introduced using H-phosphonates.