SOLVING CHALLENGING BIOORGANIC PROBLEMS BY EXCITON COUPLED CD

Authors
BEROVA N BORHAN B DONG JG GUO JS HUANG XF KARNAUKHOVA E KAWAMURA A LEU JH MATILE S NAKANISHI K RICKMAN B SU J TAN Q ZANZE I
Citation
N. Berova et al., SOLVING CHALLENGING BIOORGANIC PROBLEMS BY EXCITON COUPLED CD, Pure and applied chemistry, 70(2), 1998, pp. 377-383
Citations number
28
Categorie Soggetti
Chemistry
Journal title
Pure and applied chemistry → ACNP
ISSN journal
00334545
Volume
70
Issue
2
Year of publication
1998
Pages
377 - 383
Database
ISI
SICI code
0033-4545(1998)70:2<377:SCBPBE>2.0.ZU;2-Y
Abstract
Determination of molecular chirality is becoming increasingly importan t due to the sophistication in mode of action studies of biological re actions and the importance of chiral drugs. The exciton coupled CD, ba sed on through space coupling, is a versatile microscale method with s uperb sensitivity that can be applied to a variety of problems includi ng biopolymers and clusters in lipids. Applications of the exciton cou pled CD method to the following problems exemplify its versatility.